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The symptoms of B12 deficiency can vary between people, regardless of sex
Elevated expression of asparagine synthetase (ASNS), which transfers an amide group from glutamine to aspartate for asparagine formation, is associated with resistance to asparaginase therapy in ALL (Lomelino et al., 2017)
They start with 510 shots over a few weeks, then gradually space them farther apart, sometimes by months
As we age, collagen production slows, leading to wrinkles, sagging, and loss of elasticity
If any of these appear, discard the vial
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